Synthesis of Conjugated Dienes in Natural Compounds

Geoffrey Dumonteil (1) , Sabine Berteina-Raboin (1)

1 ICOA - Institut de Chimie Organique et Analytique

This review describes the various synthetic methods commonly used to obtain molecules possessing conjugated dienes. We focus on methods involving cross-coupling reactions using various metals such as nickel, palladium, ruthenium, cobalt, cobalt/zinc, manganese, zirconium, or iron, mainly through examples that aimed to access natural molecules or their analogues. Among the natural molecules covered in this review, we discuss the total synthesis of a phytohormone, Acid Abscisic (ABA), carried out by our team involving the development of a conjugated diene chain.

Domaines: Chimie organique

Geoffrey Dumonteil, Sabine Berteina-Raboin. Synthesis of Conjugated Dienes in Natural Compounds. Catalysts, 2022, 12 (1), pp.86. ⟨10.3390/catal12010086⟩. ⟨hal-03890848⟩