Microwave‐Assisted CH Activation of the Thiophene Ring: A Simple Approach to Access Substituted Thienopyridines

Joana Campos (1) , Mélanie Cimorelli (1) , Rihab Jemili (1) , Sabine Berteina-Raboin (1)

1 ICOA - Institut de Chimie Organique et Analytique

Abstract A practical microwave-assisted CH activation for the preparation of several phenoxythieno[3,2-b]pyridines is reported here. This new strategy is an efficient alternative to the conventional methods currently used. The optimized conditions can also be applied to a one-pot approach.

Domaines: Chimie

Joana Campos, Mélanie Cimorelli, Rihab Jemili, Sabine Berteina-Raboin. Microwave‐Assisted CH Activation of the Thiophene Ring: A Simple Approach to Access Substituted Thienopyridines. ChemistrySelect, 2021, 6 (45), pp.12556-12561. ⟨10.1002/slct.202101643⟩. ⟨hal-03717233⟩